HuagongsheHuagongshe Chemistry Print Report · For research reference only
Vinylidene chloride → 4-Bromo-3-chloro-3,4,4-trifluorobutanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Vinylidene chloride | HCID 6366 | — |
| Reactant | Cfc 113 | HCID 6428 | — |
| Reactant | 1,2-Dibromo-1-chloro-1,2,2-trifluoroethane | HCID 9634 | — |
| Reactant | Ammonium persulfate sodium formate | HCID 86749473 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-Bromo-3-chloro-3,4,4-trifluorobutanoic acid | HCID 10912127 | — |
| Product | 3,4-Dichloro-3,4,4-trifluorobutanoic acid | HCID 21836485 | — |
Reaction Steps
A one pot reaction of 1-chloro-1,2-dibromotrifluoroethane (VI) or 1,1,2-trichlorotrifluoroethane (X) with vinylidene chloride in the presence of ammonium persulfate/sodium formate/air in DMF to give 4-bromo-3-chloro-3,4,4-trifluorobutanoic acid (VIII) or 3,4-dichloro-3,4,4-trifluorobutanoic acid (XI).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05968916 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-521b14d4159a42e4b8293dea14cc8cb3 |
| Source note | uspto-grants-1999_10 |