HCID 18691585, compound → 4,6-Difluoro-5-methylbenzo[b]thiophene

HRID 1739718Notes

Reaction equation

HRID 1739718 reaction equation
C(O[CH:4](OCC)[CH2:5][S:6][C:7]1[CH:12]=[C:11]([F:13])[C:10]([CH3:14])=[C:9]([F:15])[CH:8]=1)C.C(OC(OCC)CSC1C=CC(C)=C(F)C=1)C>>[F:13][C:11]1[C:12]2[CH:4]=[CH:5][S:6][C:7]=2[CH:8]=[C:9]([F:15])[C:10]=1[CH3:14]

Participants

3

Reactant 2

HCID 18691585HCID 18691585, compoundHCID 18691589HCID 18691589, compound

Product 1

HCID 186915814,6-Difluoro-5-methylbenzo[b]thiophene

Procedure

The same procedure as in Reference Example 1 (3) is repeated, except that 1,1-diethoxy-2-(3,5-difluoro-4-methylphenylthio)ethane is substituted for the 1,1-diethoxy-2-(3-fluoro-4-methylphenylthio)ethane, to obtain 4,6-difluoro-5-methylbenzo[b]thiophene.

Sources & evidence

ORD record
ord-9d5b1ba3fde94f7aa9e92f141c43b8b1
Source dataset
uspto-grants-1999_10
Patent number
US05968935

Reaction notes

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