Triethylamine → HCID 54723389, compound

Participants

Reaction Steps

85 ml of triethylamine is agitated in a suspension containing 50 g of 4,7-dihydroxy-8-methyl-2H-1-benzopyran-2-one and 400 ml of tetrahydrofuran. A solution of 76 ml of terbutyldiphenylchlorosilane in 50 ml of tetrahydrofuran is added. The reaction mixture is agitated for 20 hours, then it is poured into a buffer solution of sodium hydrogen phosphate. Extraction is carried out with ethyl acetate, the organic phase is washed with water, dried and brought to dryness. A product is obtained which is taken up in methanol, agitation is carried out for 4 hours, followed by separating, washing and drying. 84,5 g of sought product is obtained.

Provenance & Evidence