Dimethyl Sulfoxide → HCID 21837543, compound

Participants

Reaction Steps

0.35 g of the product of Step 8, 0.87 g of dicyclohexylcarbodiimide, 0.16 ml of pyridine, 4 ml of dimethyl sulphoxide and 7.5 ml of benzene are mixed at 5° C. 0.1 ml of trifluoroacetic acid is added dropwise and the whole is stirred at room temperature for 21 hours. Dilution is carried out with ethyl acetate, and insoluble material is filtered off. The filtrate is washed with water, dried, evaporated and purified on a silica column to yield 0.28 g of the expected title product.

Provenance & Evidence