HCID 21837520, compound → 212845-61-9

HRID 1739799Notes

Reaction equation

HRID 1739799 reaction equation
[F:1][C:2]1[CH:3]=[C:4]2[C:9](=[C:10]([NH:12]C(=O)OCC3C=CC=CC=3)[CH:11]=1)[O:8][CH2:7][CH2:6][CH2:5]2>C(O)C.[Pd]>[NH2:12][C:10]1[CH:11]=[C:2]([F:1])[CH:3]=[C:4]2[C:9]=1[O:8][CH2:7][CH2:6][CH2:5]2

Participants

4

Reactant 1

HCID 21837520HCID 21837520, compound

Product 1

HCID 18414069212845-61-9

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

8.1 g of the compound of Step 3 are dissolved in 80 ml of ethanol. The solution is hydrogenated at normal pressure and room temperature in the presence of 0.39 g of palladium-on-carbon. Filtration and evaporation yield 4.6 g of a liquid which corresponds to the expected product.

Workup

  1. filtrationFiltration and evaporation yield 4.6 g of a liquid which

Sources & evidence

ORD record
ord-727fc7f2afc24c6e9bfd1257b0849dc1
Source dataset
uspto-grants-1999_10
Patent number
US05968954

Reaction notes

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