4-Benzylpiperidine → HCID 21837558, compound

HRID 1739808Notes

Reaction equation

HRID 1739808 reaction equation
[Br:1][C:2]1[CH:6]=[C:5]([CH:7]([OH:10])[CH2:8]Br)[O:4][N:3]=1.[CH2:11]([CH:18]1[CH2:23][CH2:22][NH:21][CH2:20][CH2:19]1)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>C(O)C>[CH2:11]([CH:18]1[CH2:23][CH2:22][N:21]([CH2:8][CH:7]([C:5]2[O:4][N:3]=[C:2]([Br:1])[CH:6]=2)[OH:10])[CH2:20][CH2:19]1)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

4

Reactant 2

HCID 317384-BenzylpiperidineHCID 1362697876596-55-9

Product 1

HCID 21837558HCID 21837558, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of 6.0 g of 1-(3-bromoisoxazol-5-yl)-2-bromoethanol and 11.7 ml of 4-benzylpiperidine in 150 ml of ethanol was refluxed for 2 hours.

Sources & evidence

ORD record
ord-5acf9ba7dc5e4a95a1f0c910ad5f4dcd
Source dataset
uspto-grants-1999_10
Patent number
US05968955

Reaction notes

Loading…