反应详情

A mixture of intermediate (1-a) (39 g) in ethanol (300 ml) was hydrogenated (3.9 105Pa H2) with Raney nickel (20 g) as a catalyst. After uptake of hydrogen (3 equivalents), the catalyst was filtered off and the filtrate was evaporated, yielding 34.6 g of (±)-4-[(1H-imidazol-1-yl)phenylmethyl]benzenamine (interm. 1-b).

1. customthe filtrate was evaporated