HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 15484968, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 21837476 | HCID 21837476 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 15484968 | HCID 15484968 | 100% |
Reaction Steps
A mixture of (±)-6-[hydroxy(3-fluorophenyl)methyl]-4-phenyl-2(1H)-quinolinone (11 g) of thionyl chloride (11 ml) and DCM (120 ml) was stirred at room temperature for 12 hours. The solvent was evaporated till dryness and used without further purification, yielding 11.6 g (±)-6-[chloro(3-fluorophenyl)methyl]-4-phenyl-2(1H)-quinolinone (100%) (interm. 3).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05968952 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-77f4df4e12d94366a4c46e44358bd1ad |
| Source note | uspto-grants-1999_10 |