HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → o-Tolyl-acetyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | o-Tolylacetic acid | HCID 69519 | — |
| Product | o-Tolyl-acetyl chloride | HCID 2760632 | — |
Reaction Steps
A solution of 2.0 g of o-tolylacetic acid in 27 ml of thionyl chloride is heated at reflux for 1 hour. The volatiles are evaporated in vacuo to give a residue which is concentrated from toluene three times and dried under vacuum to give 2.1 g of the desired product as a light brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05968930 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-e3398cb459324aaf8f58a255c2980d8f |
| Source note | uspto-grants-1999_10 |