HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3-Fluoro-2-methylbenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-Fluoro-2-methylbenzoic acid | HCID 246682 | — |
| Product | 3-Fluoro-2-methylbenzoyl chloride | HCID 2779240 | — |
Reaction Steps
A solution of 2.87 g of 3-fluoro-2-methylbenzoic acid in 25 ml of thionyl chloride is refluxed for 1.75 hour and the excess thionyl chloride removed under vacuum. To the residue is added toluene (several 5 times) and the toluene removed under vacuum after each addition to give 3-fluoro-2-methylbenzoyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05968930 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-205c43ff3ab54e2c92b632bc0f8d7930 |
| Source note | uspto-grants-1999_10 |