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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1740074Generated: November 1, 2026

Diethyl 2-[chloro(phenyl)methylene]malonate → 1-(4-Cyanophenyl)-4-ethoxycarbonyl-2-methyl-3-phenyl-2H-pyrazol-5-one

https://huagongshe.com/reaction/1740074

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl 2-[chloro(phenyl)methylene]malonateHCID 11219800—
Reactant1-(4-Cyanophenyl)-2-methylhydrazineHCID 21837639—
SolventTolueneHCID 1140—
Product1-(4-Cyanophenyl)-4-ethoxycarbonyl-2-methyl-3-phenyl-2H-pyrazol-5-oneHCID 2183765126.2%

Reaction Steps

4.7 g of the title compound was prepared as colorless crystals from 14.6 g of ethyl 3-chloro-2-ethoxycarbonyl-3-phenyl-acrylate, 11.0 g of 1-(4-cyanophenyl)-2-methyl-hydrazine and toluene in the same manner as in Reference Example 5.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05968967
Source datasetuspto-grants-1999_10
ORD IDord-a8b9df8b722d43b5af2a05e4ae40aedb
Source noteuspto-grants-1999_10