HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-(hydroxymethyl)-5-iodobenzoate → Methyl 3-formyl-5-iodobenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-(hydroxymethyl)-5-iodobenzoate | HCID 21837989 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | Methyl 3-formyl-5-iodobenzoate | HCID 21838328 | 55.8% |
Reaction Steps
The mixture of methyl 5-hydroxymethyl-3-iodobenzoate (5.0 g) and manganese dioxide (30.0 g) in ethyl acetate (50.0 ml) was heated under reflux for 4 hours. The magnganese dioxide was removed by filtration and the filtrate was evaporated in vacuo to give methyl 5-formyl-3-iodobenzoate (2.77 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05968985 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-8198add690444a2cb28721a0145655f5 |
| Source note | uspto-grants-1999_10 |