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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1740316Generated: October 26, 2026

Methyl 3-benzyloxycarbonylmethoxy-5-hydroxybenzoate → Methyl 3-carboxymethoxy-5-hydroxybenzoate

https://huagongshe.com/reaction/1740316

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 3-benzyloxycarbonylmethoxy-5-hydroxybenzoateHCID 21838035—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductMethyl 3-carboxymethoxy-5-hydroxybenzoateHCID 11253108103.5%

Reaction Steps

10% palladium on carbon (0.1 g) was added to a mixture of methyl 3-benzyloxycarbonylmethoxy-5-hydroxybenzoate (1 g) in methanol (20 ml) and the mixture was subjected to catalytic reduction at ambient temperature under atmospheric pressure. The catalyst was removed by filtration and the filtrate was evaporated in vacuo to give methyl 3-carboxymethoxy-5-hydroxybenzoate (0.74 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05968985
Source datasetuspto-grants-1999_10
ORD IDord-ab7f2c9943814927bc5b195fdfcfcd25
Source noteuspto-grants-1999_10