HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Tartaric acid → MS-377 L-Tartrate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Tartaric acid | HCID 444305 | — |
| Reactant | MS-377 free base | HCID 9892249 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | MS-377 L-Tartrate | HCID 9892248 | 97.3% |
Reaction Steps
To a solution of 150 mg of L-tartaric acid in 10 mL of ethanol was added a solution of 352 mg of (R)-1-(4-chlorophenyl)-3-(4-(2-methoxyethyl)piperazin-1-yl)methyl-2-pyrrolidinone in 10 mL of ethyl acetate. The mixture was stirred at room temperature and cooled. The precipitated solid was filtered and dried to give 488 mg of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05969138 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-2ecaa36e85d74e78ae82124f933679e5 |
| Source note | uspto-grants-1999_10 |