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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1740410Generated: October 31, 2026

L-Tartaric acid → MS-377 L-Tartrate

https://huagongshe.com/reaction/1740410

Reaction equation

Participants

RoleNameHCIDCharge
ReactantL-Tartaric acidHCID 444305—
ReactantMS-377 free baseHCID 9892249—
SolventEthanolHCID 702—
SolventEthyl AcetateHCID 8857—
ProductMS-377 L-TartrateHCID 989224897.3%

Reaction Steps

To a solution of 150 mg of L-tartaric acid in 10 mL of ethanol was added a solution of 352 mg of (R)-1-(4-chlorophenyl)-3-(4-(2-methoxyethyl)piperazin-1-yl)methyl-2-pyrrolidinone in 10 mL of ethyl acetate. The mixture was stirred at room temperature and cooled. The precipitated solid was filtered and dried to give 488 mg of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05969138
Source datasetuspto-grants-1999_10
ORD IDord-2ecaa36e85d74e78ae82124f933679e5
Source noteuspto-grants-1999_10