HuagongsheHuagongshe Chemistry Print Report · For research reference only
Maleic Acid → HCID 86754648, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Maleic Acid | HCID 444266 | — |
| Reactant | MS-377 free base | HCID 9892249 | — |
| Solvent | Water ethanol | HCID 19096565 | — |
| Product | HCID 86754648 | HCID 86754648 | 85.6% |
Reaction Steps
Into 62 mL of 9% water-ethanol were suspended 5.00 g of (R)-1-(4-chlorophenyl)-3-(4-(2-methoxyethyl)piperazin-1-yl)methyl-2-pyrrolidinone and 3.30 g of maleic acid. After making it homogeneous by heating under reflux, the solution was cooled. The precipitated solid was filtered and dried to give 7.10 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05969138 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-b4d513089ad14e5cb7cf4d2c928b3afc |
| Source note | uspto-grants-1999_10 |