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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1740539Generated: October 28, 2026

Sarcosine → Creatine

https://huagongshe.com/reaction/1740539

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSarcosineHCID 1088—
ReactantCarbamimidic acid, methyl ester, hydrochloride (1:1)HCID 3083899—
ProductCreatineHCID 586—

Reaction Steps

The reaction of sarcosine with O-methylisourea hydrochloride, described by E. Schutte in Hoppe-Seylers Z. Physiol. Chemie 279 (1943) 52-59, affords creatine in a yield of only 21%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05969182
Source datasetuspto-grants-1999_10
ORD IDord-1e8edc502378488c8e41b8272ade6bcc
Source noteuspto-grants-1999_10