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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1740627Generated: November 2, 2026

1-(2-Bromo-4-pyridyl)-2,3-bis(hydroxymethyl)-6,7-dimethoxynaphthalene → 1-(2-Amino-4-pyridyl)-2,3-bis(hydroxymethyl)-6,7-dimethoxynaphthalene

https://huagongshe.com/reaction/1740627

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Bromo-4-pyridyl)-2,3-bis(hydroxymethyl)-6,7-dimethoxynaphthaleneHCID 10692560—
ReactantPhthalimide potassium saltHCID 24194345—
Product1-(2-Amino-4-pyridyl)-2,3-bis(hydroxymethyl)-6,7-dimethoxynaphthaleneHCID 22007424—

Reaction Steps

1-(2-Bromo-4-pyridyl)-2,3-bis(hydroxymethyl)-6,7-dimethoxynaphthalene and potassium phthalimide are treated in the same manner as in Example 6-(2) to give 1-(2-amino-4-pyridyl)-2,3-bis(hydroxymethyl)-6,7-dimethoxynaphthalene which is a hydrolysis product of 1-(2-phthalimide-4-pyridyl)-2,3-bis(hydroxymethyl)-6,7-dimethoxynaphthalene and listed in Table 6.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05969140
Source datasetuspto-grants-1999_10
ORD IDord-618137b7544c4916a51ebf23df412279
Source noteuspto-grants-1999_10