2-(4'-Chlorobenzoyl)benzoic acid → 1-[2-{4-(4-chlorophenyl)-1(2H)-phthalazinon-2-yl}-4-pyridyl]-3-hydroxymethyl-6,7-diethoxynaphthalene

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	2-(4'-Chlorobenzoyl)benzoic acid	HCID 66564	—
Edukt	1-(2-Hydrazino-4-pyridyl)-3-hydroxymethyl-6,7-diethoxynaphthalene	HCID 22007332	—
Lösungsmittel	Ethylene Glycol	HCID 174	—
Produkt	1-[2-{4-(4-chlorophenyl)-1(2H)-phthalazinon-2-yl}-4-pyridyl]-3-hydroxymethyl-6,7-diethoxynaphthalene	HCID 22007338	85,3%

Reaktionsschritte

1-(2-Hydrazino-4-pyridyl)-3-hydroxymethyl-6,7-diethoxynaphthalene (177 mg), 1-carboxy-2-(4-chlorophenylcarbonyl)benzene (137 mg) and ethylene glycol (1 ml) are treated in the same manner as in Example 104-(3) to give 1-[2-{4-(4-chlorophenyl)-1(2H)-phthalazinon-2-yl}-4-pyridyl]-3-hydroxymethyl-6,7-diethoxynaphthalene (247 mg), which is listed in Table 14.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US05969140
Quelldatensatz	uspto-grants-1999_10
ORD ID	ord-99d600b149864155ba2cb918c06a2212
Quellennotiz	uspto-grants-1999_10