N,N-Dimethylcyclohexylamine → HCID 10955654, compound

Participants

Reaction Conditions

Reaction Steps

113 g (1 mol) of ε-caprolactam (purity >99% by weight) are dissolved in 200 ml of toluene in a round-bottom flask. 127 g (1 mol) of N,N-dimethylcyclohexylamine are introduced into this. Then, at 40-70° C., 164.2 g (1 mol) of octanoyl chloride (purity 99% by weight) are added dropwise. The reaction mixture is then stirred at 65-70° C. for one hour. Then, to remove the ammonium salt produced, it is washed first once with 130 ml of hot water and then with 10 ml of concentrated HCl dissolved in 130 ml of hot water. It is subsequently washed 3 more times with 130 ml of hot water in order to maintain a pH of 5-7 in the reaction mixture. The solvent is distilled off under reduced pressure (water pump) at 70-80° C. N-octanoylcaprolactam is obtained as a yellow liquid in 93% yield with a purity of 98%.

Provenance & Evidence