Ammonium → Tert-butyl 3-(2-(pyridin-3-yl)ethyl)piperazine-1-carboxylate

HRID 174071Notes

Reaction equation

HRID 174071 reaction equation
[CH3:36][CH2:37][OH:38].[CH:1]([O-:2])=[O:3].[NH4+:4].[OH-:39].[OH-:41].[Pd+2:40].[n:5]1[cH:6][c:7]([CH2:11][CH2:12][CH:13]2[N:14]([C:26]([O:27][CH2:28][c:29]3[cH:30][cH:31][cH:32][cH:33][cH:34]3)=[O:35])[CH2:15][CH2:16][N:17]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:18]2)[cH:8][cH:9][cH:10]1>>[n:5]1[cH:6][c:7]([CH2:11][CH2:12][CH:13]2[NH:14][CH2:15][CH2:16][N:17]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:18]2)[cH:8][cH:9][cH:10]1

Participants

7

Reactant 6

HCID 223AmmoniumHCID 283FormateHCID 702EthanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 596715351-Benzyl 4-tert-butyl 2-(2-(pyridin-3-yl)ethyl)piperazine-1,4-dicarboxylate

Product 1

HCID 59671489Tert-butyl 3-(2-(pyridin-3-yl)ethyl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-fb8da0860641477cb66d810c05350288
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…