(2S,3S)-3-Amino-1-tert-butoxycarbonyl-2-phenylpiperidine → (2S,3S)-1-tert-Butoxycarbonyl-3-[(9-methoxy-6,7-dihydro-5H-[1,2,3,4]tetrazolo[5,1-a][2]benzazepin-10-yl)methyl]amino-2-phenylpiperidine

HRID 1740737Notes

Reaction equation

[CH3:1][O:2][C:3]1[C:4]([CH:17]=O)=[CH:5][C:6]2[C:12]3=[N:13][N:14]=[N:15][N:11]3[CH2:10][CH2:9][CH2:8][C:7]=2[CH:16]=1.[NH2:19][C@H:20]1[CH2:25][CH2:24][CH2:23][N:22]([C:26]([O:28][C:29]([CH3:32])([CH3:31])[CH3:30])=[O:27])[C@H:21]1[C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1.C(OC(N1CCC[C@H](NCC2C=C3C(CCC4N3N=NN=4)=CC=2OC)[C@@H]1C1C=CC=CC=1)=O)(C)(C)C>>[C:29]([O:28][C:26]([N:22]1[CH2:23][CH2:24][CH2:25][C@H:20]([NH:19][CH2:17][C:4]2[C:3]([O:2][CH3:1])=[CH:16][C:7]3[CH2:8][CH2:9][CH2:10][N:11]4[N:15]=[N:14][N:13]=[C:12]4[C:6]=3[CH:5]=2)[C@@H:21]1[C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1)=[O:27])([CH3:32])([CH3:30])[CH3:31]