(2S,3S)-1-tert-Butoxycarbonyl-3-[(7-methoxy-1,2,4,5-tetrahydroimidazo[1,2-a]quinolin-8-yl)methyl]amino-2-phenylpiperidine → (2S,3S)-3-[(7-Methoxy-1,2,4,5-tetrahydroimidazo[1,2-a]quinolin-8-yl)methyl]amino-2-phenylpiperidine trihydrochloride
Reaction equation
C(OC([N:8]1[CH2:13][CH2:12][CH2:11][C@H:10]([NH:14][CH2:15][C:16]2[CH:25]=[C:24]3[C:19]([CH2:20][CH2:21][C:22]4[N:23]3[CH2:26][CH2:27][N:28]=4)=[CH:18][C:17]=2[O:29][CH3:30])[C@@H:9]1[C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1)=O)(C)(C)C.[ClH:37].Cl.COC1C=C2C(=CC=1CN[C@H]1CCCN[C@H]1C1C=CC=CC=1)N1N=NN=C1CC2>>[ClH:37].[ClH:37].[ClH:37].[CH3:30][O:29][C:17]1[CH:18]=[C:19]2[C:24](=[CH:25][C:16]=1[CH2:15][NH:14][C@H:10]1[CH2:11][CH2:12][CH2:13][NH:8][C@H:9]1[C:31]1[CH:32]=[CH:33][CH:34]=[CH:35][CH:36]=1)[N:23]1[CH2:26][CH2:27][N:28]=[C:22]1[CH2:21][CH2:20]2Participants
3
Reactant 2
Product 1
Procedure
This compound was prepared from Compound 16 in the same manner of Compound 8.
Sources & evidence
- ORD record
- ord-7a37d25fb5754d1387f5fc5d3a45c6bf
- Source dataset
- uspto-grants-1999_10
- Patent number
- US05972930
Reaction notes
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