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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1740774Generated: November 1, 2026

Morpholine → 5-(Morpholine-4-carbonyl)-2-pyridinecarboxylic acid, methyl ester

https://huagongshe.com/reaction/1740774

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
Reactant5-Chlorocarbonyl-pyridine-2-carboxylic acid methyl esterHCID 15121177—
Product5-(Morpholine-4-carbonyl)-2-pyridinecarboxylic acid, methyl esterHCID 20622307—

Reaction Steps

In step b, the acid chloride 11 is amidated with morpholine 12 by techniques and procedures well known and appreciated by one of ordinary skill in the art to give the corresponding 5-(morpholine-4-carbonyl)-2-pyridinecarboxylic acid, methyl ester 13.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05972897
Source datasetuspto-grants-1999_10
ORD IDord-efaf2a2220a941e3839dc311e0fe5b57
Source noteuspto-grants-1999_10