Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1740776Generated: October 25, 2026

Hydrochloric Acid → 6-(Morpholine-4-carbonyl)nicotinic acid

https://huagongshe.com/reaction/1740776

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant6-(Morpholine-4-carbonyl)nicotinic acid, t-butyl esterHCID 10085718—
SolventNitromethaneHCID 6375—
Product6-(Morpholine-4-carbonyl)nicotinic acidHCID 10105514—

Reaction Steps

In step c, the t-butyl ester functionality of 16 is hydrolyzed, with for example, HCl in nitromethane, to give the corresponding 6-(morpholine-4-carbonyl)nicotinic acid 17.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05972897
Source datasetuspto-grants-1999_10
ORD IDord-4993192f08334953a262894f85194efa
Source noteuspto-grants-1999_10