Sodium Sulfate → 16-Methoxymethoxyhexadecanol

Participants

Reaction Steps

To a solution of 3.0 g of ethyl 16-methoxymethoxyhexadecanoate in 50 ml of tetrahydrofuran was added under ice-cooling 1.5 g of lithium aluminum hydride and the mixture was stirred for one hour. After a saturated aqueous solution of sodium sulfate was added, the insolubles precipitated out were filtered off and distilled under reduced pressure. The residue was chromatographed over a silica gel column to afford the title compound as a colorless oily substance.

Provenance & Evidence