Hydrazine hydrate (1:1) → HCID 21833206, compound

Participants

Reaction Steps

To a suspension of 0.97 g of N-(16-methoxymethoxyhexadecyl)phthalimide in 50 ml of ethanol was added 0.4 ml of hydrazine monohydrate and the mixture was heated under reflux for 2 hours. The reaction solution was distilled under reduced pressure. The residue was diluted with chloroform, washed with a 1N aqueous solution of sodium hydroxide, dried over anhydrous sodium sulfate and then distilled under reduced pressure. The residue was chromatographed over a silica gel column to afford the title compound as a colorless oily substance.

Provenance & Evidence