1-(2-Dimethylaminoethoxy)-3-nitrobenzene → 3-[2-(Dimethylamino)ethoxy]aniline

Participants

Reaction Steps

To a solution of 1-(2-dimethylaminoethoxy)-3-nitrobenzene (4.64 g, 22 mmol) in ethanol (200 ml) was added 10% palladium catalyst on charcoal (1 g). The reaction mixture was hydrogenated at atmospheric pressure for 2 hours, then filtered through kieselguhr and evaporated under reduced pressure to give the product as a yellow oil (4.0 g, 100%).

Provenance & Evidence