HCID 21833074, compound → HCID 21833100, compound

HRID 1740795Notes

Reaction equation

HRID 1740795 reaction equation
[Si:1]([O:8][CH2:9][CH2:10][O:11][C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([N+:18]([O-])=O)[CH:13]=1)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2]>C(O)C.[Pd]>[Si:1]([O:8][CH2:9][CH2:10][O:11][C:12]1[CH:13]=[C:14]([CH:15]=[CH:16][CH:17]=1)[NH2:18])([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2]

Participants

4

Reactant 1

HCID 21833074HCID 21833074, compound

Product 1

HCID 21833100HCID 21833100, compoundYield 94%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

To a solution of 1-(2-t-butyldimethylsilyloxyethoxy)-3-nitrobenzene (7.918 g, 27 mmol) in ethanol (150 ml) was added 10% palladium catalyst on charcoal (2 g) and the reaction mixture was hydrogenated at atmospheric pressure for 2 hours. It was then filtered through kieselguhr and evaporated under reduced pressure to yield the product as a yellow oil (6.707 g, 94%)

Workup

  1. filtrationIt was then filtered through kieselguhr
  2. customevaporated under reduced pressure

Sources & evidence

ORD record
ord-59eb817122d24ce9bba2310fd4624108
Source dataset
uspto-grants-1999_10
Patent number
US05972937

Reaction notes

Loading…