HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-dimethyl-3-nitrobenzamide → 3-Amino-N,N-dimethylbenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-dimethyl-3-nitrobenzamide | HCID 347759 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-Amino-N,N-dimethylbenzamide | HCID 424774 | 87% |
Reaction Steps
N,N-Dimethyl-3-nitrobenzamide (D23) (0.94 g, 4.8 mmol) was hydrogenated in ethanol (100 ml) over 10% Palladium-Charcoal (0.25 g) for 1 hour. The catalyst was removed by filtration through Kieselguhr, and the filtrate concentrated in vacuo to afford the title compound as a light brown solid (0.68 g, 87%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05972937 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-d682567f8ca04867be9255ee5ab9e9a9 |
| Source note | uspto-grants-1999_10 |