HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → 4-methyl-6-(3-methylbutyl)-2-Pyridinamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Reactant | 4-Methyl-6-(3-methylbutyl)-2-(2,5-dimethylpyrrol-1-yl)pyridine | HCID 21834403 | — |
| Solvent | Water ethanol | HCID 19096565 | — |
| Product | 4-methyl-6-(3-methylbutyl)-2-Pyridinamine | HCID 9794039 | — |
Reaction Steps
By analogy to Example 56, Step B, 4-methyl-6-(3-methylbutyl)-2-(2,5-dimethylpyrrol-1-yl)pyridine was treated with 4.6 equivalents of hydroxylamine hydrochloride and 2.8 equivalents of potassium hydroxide in refluxing ethanol/water to yield 2-amino-4-methyl-6-(3-methylbutyl)pyridine as an amber oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05972975 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-f19eeca8718e444f876def2fe2f4e54a |
| Source note | uspto-grants-1999_10 |