HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1741018Generated: October 30, 2026
Sodium methanethiolate → (E)-4-[2-[2-[[(p-Hydroxyphenyl)sulfonyl]amino]phenyl]ethenyl]pyridine
https://huagongshe.com/reaction/1741018
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium methanethiolate | HCID 4378561 | — |
| Reactant | Hmn 154 | HCID 6366736 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | (E)-4-[2-[2-[[(p-Hydroxyphenyl)sulfonyl]amino]phenyl]ethenyl]pyridine | HCID 21834523 | 9.9% |
Reaction Steps
In DMF was dissolved 2.00 g of the (E)-4-[2-[2-[[(p-methoxyphenyl)sulfonyl]amino]phenyl]ethenyl]pyridine obtained in Example 3, followed by addition of 1.91 g of sodium methanethiolate, and the mixture was stirred at 100° C. overnight and then after-treated. The resulting crystals were recrystallized from methanol to provide 0.19 g of the title compound (white powders).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05972976 |
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| Source dataset | uspto-grants-1999_10 |
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| ORD ID | ord-7b3a3dcd242e450f92af971fb91c5a74 |
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| Source note | uspto-grants-1999_10 |
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