4-Carboxyphenylboronic Acid → 4'-(5-Methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carboxylic acid

HRID 1741039Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1741039
Br[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:12]=[C:11]([CH3:13])[O:10][N:9]=2)=[CH:4][CH:3]=1.B([C:17]1[CH:25]=[CH:24][C:20]([C:21]([OH:23])=[O:22])=[CH:19][CH:18]=1)(O)O>>[CH3:13][C:11]1[O:10][N:9]=[C:8]([C:5]2[CH:6]=[CH:7][C:2]([C:17]3[CH:25]=[CH:24][C:20]([C:21]([OH:23])=[O:22])=[CH:19][CH:18]=3)=[CH:3][CH:4]=2)[N:12]=1

Komponenten

3

Edukt 2

HCID 3121834-Carboxyphenylboronic AcidHCID 8235603-(4-Bromophenyl)-5-methyl-1,2,4-oxadiazole

Produkt 1

HCID 218337574'-(5-Methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carboxylic acid

Versuchsvorschrift

The title compound was prepared from 1-bromo-4-(5-methyl-1,2,4-oxadiazol-3-yl)benzene [EP 0533268A1] (0.58 g) and 4-boronobenzoic acid (0.4 g) as described in Description 11 as a white solid (0.64 g, 97%).

Quellen und Nachweise

ORD-Eintrag
ord-e4cd8f87d6d348f5b5407134a36f250c
Quelldatensatz
uspto-grants-1999_10
Patentnummer
US05972951

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