HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxy-4-nitroaniline → HCID 21834796, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxy-4-nitroaniline | HCID 7337 | — |
| Reactant | Chlorobenzene | HCID 7964 | — |
| Reactant | Tert-Butyl nitrite | HCID 10906 | — |
| Catalyst | Copper | HCID 23978 | — |
| Product | HCID 21834796 | HCID 21834796 | — |
Reaction Steps
2-Methoxy4-nitroaniline 5 and chlorobenzene are heated in the presence of t-butylnitrite and copper powder to give 2-(4-chlorophenyl)-5-nitroanisole 6. Hydrogenation of 6 with platinum oxide in methanol (a base such as morpholine may be used) provides the desired biphenyl amine 3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05973008 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-1fec073ffe734c35b92868f1b597a6d3 |
| Source note | uspto-grants-1999_10 |