2-Chlorobenzoyl isocyanate → HCID 21834793, compound

Participants

Reaction Steps

To a stirred solution of 2-chlorobenzoylisocyanate (0.2 g, 1.1 mmol) in xylenes (40 ml) was added a solution of 4-(4-chlorophenyl)-3-methoxyaniline (0.2 g, 0.9 mmol) in xylenes (ml). The mixture was stirred at ambient temperature for 2.5 hours then diluted with n-heptane (60 ml) and stirred for an additional one-half hour. The resulting precipitate was collected by filtration and washed with cold pentane to provide 2-chloro-N-[{(2-methoxy4'-chloro[1,1'-biphenyl]-4-yl)amino}carbonyl]benzamide, m.p. 178-179° C. (Compound A).

Provenance & Evidence