HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoic Acid → 3-Cyclohexene-1-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoic Acid | HCID 243 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Product | 3-Cyclohexene-1-carboxylic acid | HCID 20903 | — |
| Product | 3-Cyclohexene-1-carbonyl chloride | HCID 523058 | — |
Reaction Steps
The 4-hydroxy group of 4-hydroxybenzoic acid is protected by reacting 4-hydroxybenzoic acid, 5 g (0.036 mol), obtained commercially, with benzyl chloride, 5.1 g (0.04 mol) in ethanol:water (1:1) containing 5 g K2CO3 (0.04 mol) at a temperature of 30 degrees C. for 12 hours. The 4-PgO benzoic acid is converted to the acid chloride using thionyl chloride by a procedure similar to that employed for producing 3-cyclohexene carboxylic acid chloride from 3-cyclohexene carboxylic acid in Example I.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05973033 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-4945247369fd4481aba9888a9631580c |
| Source note | uspto-grants-1999_10 |