HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethylformamide → 4-Chloroquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethylformamide | HCID 12051 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | quinolin-4-ol | HCID 178516385 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-Chloroquinoline | HCID 69140 | — |
Reaction Steps
reacting the 4-hydroxyquinoline of formula (11) with thionyl chloride in the presence N,N-dimethylformamide or N,N-diethylformamide to obtain a 4-chloroquinoline of formula (12), ##STR11##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05973153 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-7dde05b49a7149fdae7baca198563950 |
| Source note | uspto-grants-1999_10 |