HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tributylphosphine → 5-{4-[2-(2-Pyridylmethyleneaminooxy)ethoxy]benzyl}-3-tritylthiazolidine-2,4-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tributylphosphine | HCID 13831 | — |
| Reactant | 5-(4-Hydroxybenzyl)-3-triphenylmethylthiazolidine-2,4-dione | HCID 2818126 | — |
| Reactant | 2-(2-Pyridylmethyleneaminooxy)ethanol | HCID 54166030 | — |
| Reactant | 1,1'-(Azodicarbonyl)dipiperazine | HCID 54471820 | — |
| Product | 5-{4-[2-(2-Pyridylmethyleneaminooxy)ethoxy]benzyl}-3-tritylthiazolidine-2,4-dione | HCID 73847986 | 55% |
Reaction Steps
Following a procedure similar to that described in Example 3(a), but using 498 mg of 2-(2-pyridylmethyleneaminooxy)ethanol (prepared as described in Preparation 4), 1.13 g of 5-(4-hydroxybenzyl)-3-tritylthiazolidine-2,4-dione, 0.75 ml of tributylphosphine and 693 mg of 1,1'-(azodicarbonyl)dipiperazine, 0.82 g of the title compound was obtained as a foam-like solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05972959 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-33366c427cde4d12baf66692f8b0c63a |
| Source note | uspto-grants-1999_10 |