Triphenylphosphine → 5-(4-{2-[1-(4-Biphenylyl)ethylideneaminooxy]ethoxy}benzyl)-3-tritylthiazolidine-2,4-dione

Participants

Role	Name	HCID	Charge
Reactant	Triphenylphosphine	HCID 11776	—
Reactant	ethyl N-ethoxycarbonyliminocarbamate	HCID 220568	—
Reactant	5-(4-Hydroxybenzyl)-3-triphenylmethylthiazolidine-2,4-dione	HCID 2818126	—
Reactant	2-[1-(4-Biphenylyl)ethylideneaminooxy]ethanol	HCID 54400349	—
Product	5-(4-{2-[1-(4-Biphenylyl)ethylideneaminooxy]ethoxy}benzyl)-3-tritylthiazolidine-2,4-dione	HCID 86751801	71.5%

Reaction Steps

Following a procedure similar to that described in Example 1(a), but using 170 mg of 2-[1-(4-biphenylyl)-ethylideneaminooxy]ethanol (prepared as described in Preparation 15), 238 mg of 5-(4-hydroxybenzyl)-3-tritylthiazolidine-2,4-dione, 175 mg of triphenylphosphine and 116 mg of diethyl azodicarboxylate, 257 mg of the title compound were obtained as a crystalline powder, melting at 145° C.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US05972959
Source dataset	uspto-grants-1999_10
ORD ID	ord-84d6e88a3c9c41269397b16ea3e58b4f
Source note	uspto-grants-1999_10