Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1741469Generated: October 25, 2026

Hydrochloric Acid → 1-(2-naphthylmethyl)-1H-imidazol-5-ylacetic acid hydrochloride

https://huagongshe.com/reaction/1741469

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant2-[1-(Naphth-2-ylmethyl)-1H-imidazol-5-yl]acetic acid methyl esterHCID 53806866—
Product1-(2-naphthylmethyl)-1H-imidazol-5-ylacetic acid hydrochlorideHCID 70206205—

Reaction Conditions

Temperature55 °C

Reaction Steps

2-[1-(Naphth-2-ylmethyl)-1H-imidazol-5-yl]acetic acid methyl ester (0.92 g, 3.28 mmol ) was dissolved in 2.5m hydrochloric acid (50 ml ) and heated at 55° C. for 3 h. After this time, the solution was evaporated in vacuo to give the title compound as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05972984
Source datasetuspto-grants-1999_10
ORD IDord-7041c7e805564b55964f8967b3fb0f40
Source noteuspto-grants-1999_10