Hydrogen Peroxide → HCID 67848941, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 10 (37.3 g, 0.095 mol) in EtOAc (1 l ) under N2 stirred at r.t. was added NaWO4 ·2H2O (2.9 g, 0.009 mol) in H2O (45 mol). After 15 min., 30% H2O2 (27 ml, 0.26 mol) was added dropwise. After addition, the solution was heated at 40° C. After 3.5 h, Na2SO3 (12 g, 0.095 mol) in H2O (12.5 ml) was added until a negative starch iodide test was observed. The layers were separated, extracted with EtOAc (1×) and the organic layers were washed with saturated NaCl, dried, filtered and concentrated to dryness to yield 39.9 g (98%) of 11.

Provenance & Evidence