HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylmorpholine → HCID 19010477, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylmorpholine | HCID 7972 | — |
| Reactant | Cyclopentyl chloroformate | HCID 2735892 | — |
| Reactant | HCID 19010476 | HCID 19010476 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 19010477 | HCID 19010477 | — |
Reaction Steps
To the solution of the amine from Step 2 in CH2Cl2 (4 ml) at r.t. was successively added N-methylmorpholine (130 μl, 3 eq.) followed by cyclopentylchloroformate (176 μl, 3 eq.). After 15 mins, the mixture was quenched with aq NH4Cl and worked up in the usual manner. Chromatography on silica gel (EtOAc/toluene, 1:9) afforded the title carbamate (170 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05334597 |
| Source dataset | uspto-grants-1994_08 |
| ORD ID | ord-eb9c824da1d3418aac62842a78441837 |
| Source note | uspto-grants-1994_08 |