HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic acid, 2-(triphenylphosphoranylidene)-, ethyl ester → HCID 14360978, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic acid, 2-(triphenylphosphoranylidene)-, ethyl ester | HCID 70670 | — |
| Reactant | 2-Quinolinecarboxaldehyde | HCID 79619 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 14360978 | HCID 14360978 | 77.6% |
Reaction Steps
A solution of quinoline-2-carboxaldehyde (1.51 g, 9.65 mmol) in THF (15 ml) was heated under reflux with (carbethoxymethylene) triphenylphosphorane (3.36 g). After 2 hr, the THF was removed and the residue was chromatographed using toluene/EtOAc (18:1) as eluent to afford 1.70 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05334597 |
| Source dataset | uspto-grants-1994_08 |
| ORD ID | ord-25c64f32f53e4f0baa36c66874afe8c8 |
| Source note | uspto-grants-1994_08 |