HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 11728615, compound → Ethyl 4-[1-(3-aminobenzoyl)indolizin-3-yl]butyrate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 11728615 | HCID 11728615 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | HCID 23496530 | HCID 23496530 | — |
| Product | Ethyl 4-[1-(3-aminobenzoyl)indolizin-3-yl]butyrate | HCID 10904244 | 100.8% |
Reaction Steps
To a solution of ethyl 4-[1-(3-nitrobenzoyl)-indolizin-3-yl]butyrate (350 mg) in dioxane-ethanol (1:1; ml) was added 10% palladium on carbon (210 mg) and hydrogenated under 4 atm of hydrogen for 4 hours, and then filtered through a celite. Removal of the solvent gave ethyl 4-[1-(3-aminobenzoyl)indolizin-3-yl]butyrate (325 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05334716 |
| Source dataset | uspto-grants-1994_08 |
| ORD ID | ord-dacc192f636f4fd7b942611a6f3e5e80 |
| Source note | uspto-grants-1994_08 |