Hydrochloric Acid → HCID 19010787, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of methyl 2-methoxy-4-(2-methyl-1propenyl)benzoate (178 mg) in methanol (3 ml) and 1,4-dioxane (3 ml) was added 1N aqueous solution of sodium hydroxide (2 ml). The mixture was stirred at 50° C. for 3 hours, and then poured into a mixture of ethyl acetate and 0.5N hydrochloric acid. The organic layer was separated, washed with water and brine, dried over magnesium sulfate. Evaporation of the solvent gave 2-methoxy-4-(2-methyl-1propenyl)benzoic acid (142 mg) as solid.

Provenance & Evidence