HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl isocyanate → 4-Ethyl-2-propyl semicarbazide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl isocyanate | HCID 8022 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | Hydrazine, propyl-, ethanedioate (1:1) | HCID 96079 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 4-Ethyl-2-propyl semicarbazide | HCID 19010929 | — |
Reaction Steps
To a stirred slurry of 3.35 g (20 mmol) of n-propylhydrazine oxalate and 2.24 g (20 mmol) of sodium carbonate in 50 mL of water and 10 mL of tetrahydrofuran (THF) was added 1.7 mL (21.5 mmol) of ethyl isocyanate. The mixture was stirred at room temperature for 16 h and evaporated in vacuo to leave crude 4-ethyl-2-propyl semicarbazide as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05334726 |
| Source dataset | uspto-grants-1994_08 |
| ORD ID | ord-5f57321e62a6428397dbd99332e3be1a |
| Source note | uspto-grants-1994_08 |