HCID 15125738, compound → HCID 15125760, compound

HRID 1741876Notes

Reaction equation

HRID 1741876 reaction equation
[OH:1][CH2:2][C:3]1[CH:4]=[C:5]([CH:18]=[CH:19][CH:20]=1)[O:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[CH2:13][C:14]([O:16][CH3:17])=[O:15].[Cr](Cl)([O-])(=O)=O.[NH+]1C=CC=CC=1>C(Cl)Cl>[CH:2]([C:3]1[CH:4]=[C:5]([CH:18]=[CH:19][CH:20]=1)[O:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[CH2:13][C:14]([O:16][CH3:17])=[O:15])=[O:1]

Participants

4

Reactant 2

HCID 15125738HCID 15125738, compoundHCID 178418287HCID 178418287, compound

Product 1

HCID 15125760HCID 15125760, compoundYield 85.4%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Methyl 2-(3-hydroxymethylphenoxy)phenylacetate (10.0 g, preparared as described in Example 17) and celite (10 g) were mixed in methylene chloride (100 ml), and pyridinium chlorochromate (15.85 g) was added in one portion. After stirring at room temperature for 2.5 hours, the mixture was filtered and the filtrate was evaporated to give methyl 2-(3-formylphenoxy)phenylacetate as an orange oil (8.48 g), which was pure enough to use without further purification.

Workup

  1. filtrationthe mixture was filtered
  2. customthe filtrate was evaporated

Sources & evidence

ORD record
ord-8e189bec96844ec49a5b9d7d0a15d868
Source dataset
uspto-grants-1994_08
Patent number
US05334748

Reaction notes

Loading…