反应详情

3,4-(Dimethylmethylenedioxy)-2-hydroxy-5-hexen-1-yl p-toluenesulfonate (17.88 g) was dissolved in ml of methanol, and 17.11 g of anhydrous sodium carbonate was added at room temperature, followed by stirring the mixture for 15 minutes. The reaction mixture was filtered through Celite, and crystals were washed with diethyl ether. After the filtrate was concentrated, the solid was filtered through a silica gel column. The filtrate was concentrated under reduced pressure to obtain 7.87 g of 1,2-epoxy-3,4-(dimethylmethylenedioxy)-5-hexene having the following properties.

1. additionwas added at room temperature
2. filtrationThe reaction mixture was filtered through Celite, and crystals
3. washwere washed with diethyl ether
4. concentrationAfter the filtrate was concentrated
5. filtrationthe solid was filtered through a silica gel column
6. concentrationThe filtrate was concentrated under reduced pressure