HCID 10855741, compound → HCID 19011016, compound

HRID 1741971Notes

Reaction equation

HRID 1741971 reaction equation
[C:1]([O:4][CH:5]1[CH:10]([O:11][Si:12]([C:15]([CH3:18])([CH3:17])[CH3:16])([CH3:14])[CH3:13])[CH2:9][C:8](=O)[CH:7]([CH2:20][OH:21])[CH:6]1[O:22][Si:23]([C:26]([CH3:29])([CH3:28])[CH3:27])([CH3:25])[CH3:24])(=[O:3])[CH3:2].COC[O:33][CH:34]1CC(=O)CC[CH2:35]1>>[C:1]([O:4][CH:5]1[CH:10]([O:11][Si:12]([C:15]([CH3:17])([CH3:16])[CH3:18])([CH3:13])[CH3:14])[CH2:9][C:8]2=[CH:35][C:34](=[O:33])[O:21][CH2:20][CH:7]2[CH:6]1[O:22][Si:23]([C:26]([CH3:29])([CH3:28])[CH3:27])([CH3:24])[CH3:25])(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 10855741HCID 10855741, compoundHCID 19010980HCID 19010980, compound

Product 1

HCID 19011016HCID 19011016, compoundYield 34%

Procedure

Example 4 was repeated except that 4-acetoxy-3,5-bis(tert-butyldimethylsilyloxy)-2-hydroxymethylcyclohexanone was used instead of 2-hydroxymethyl-3,4-dimethylmethylenedioxy)-5-(methoxymethoxy)cyclohexanone to give 7-acetoxy-6,8-bis(tert-butyldimethylsilyloxy)-1,5,6,7,8,8a-hexahydro-3H-2-benzopyran-3-one having the following property (yield 34%).

Sources & evidence

ORD record
ord-82bb390dd5754d9197ec0e9b4781004b
Source dataset
uspto-grants-1994_08
Patent number
US05334740

Reaction notes

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