Methanesulfonyl chloride → HCID 54238111, compound

Participants

Reaction Steps

The obtained ethyl (2-hydroxymethyl-3,4-(dimethylmethylenedioxy)-5-(1-ethoxyethoxy)cyclohexylidene)acetate was dissolved in 5 ml of pyridine, and 0.12 g of methanesulfonyl chloride was added, followed by stirring the mixture overnight at room temperature. The reaction liquid was concentrated under reduced pressure, diluted with diethyl ether, washed with a saturated sodium hydrogen carbonate aqueous solution and a saturated sodium chloride aqueous solution in sequence, dried over anhydrous magnesium sulfate, and then concentrated conducted under reduced pressure. The obtained residue was purified by silica gel column chromatography to give 0.282 g of ethyl (2-methylene-3,4-(dimethylmethylenedioxy)-5-(1-ethoxyethoxy)cyclohexylidene)acetate having the following property.

Provenance & Evidence