Diethyl Ether → HCID 54269160, compound

Participants

Reaction Steps

Ethyl (2-methylene-3,4-(dimethylmethylenedioxy)-5-(1-ethoxyethoxy)cyclohexylidene)acetate was dissolved in 5 ml of ethanol, and a catalytic amount of pyridinium p-toluenesulfonate was added, followed by stirring at room temperature for 15 minutes. A sodium hydrogen carbonate aqueous solution was added to the reaction mixture, and extraction was conducted with diethyl ether. The extract was washed with a saturated sodium chloride aqueous solution, dried over anhydrous magnesium sulfate, and concentrated under reduced pressure. The obtained residue was purified by silica gel column chromatography to afford 0.202 g of ethyl (2-methylene-3,4-(dimethylmethylenedioxy)-5-hydroxycyclohexylidene)acetate having the following property.

Provenance & Evidence